Kimberly Mueller, Ph.D., CCC-SLP
62 Goodnight Hall @ 12:00 pm - 1:00 pm
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Episodes of lucidity (EL) in Alzheimer’s disease and related dementias (ADRD) are defined as unexpected, spontaneous, and meaningful communication or connectedness in individuals thought to have lost the capacity for coherent interaction due to a progressive neurodegenerative process. While evidence for ELs has traditionally been limited to case studies and retrospective reports, recent initiatives from the National Institute on Aging have spurred studies aimed at operationalizing and directly measuring ELs. Understanding ELs could provide new insights into cognitive decline mechanisms, suggest potential therapeutic approaches, and improve caregiver strategies. Moreover, documenting ELs can reshape societal views on personhood in dementia. This presentation will introduce a research framework to study ELs, including guiding principles, definitions, proposed measurement methods, and areas needing further exploration. A study at the University of Wisconsin–Madison using video observational data in a hospice care setting will be highlighted, along with the perspectives of caregivers, staff, and individuals with dementia on the ethical considerations and research priorities.









