Prosem Lecture: Sensitivity to Low-frequency Binaural Cues in Children and Adults

Mohammad Maarefvand, Ph.D.
62 Goodnight Hall
@ 12:00 pm - 1:00 pm
Learn more about Prosem

In standard clinical audiological practice, individuals with severe-to-profound hearing loss receive cochlear implants in one or both ears. Recent advances in the field recognize that some patients have residual low-frequency acoustic hearing, making them eligible for Electric-Acoustic Stimulation (EAS). EAS combines high-frequency electric hearing (through a cochlear implant) with low-frequency acoustic hearing (through a hearing aid) in the same ear. Studies in adults have reported benefits from EAS, including improved speech understanding in noise and sound localization. Little is known about benefits from EAS for children. Moreover, benchmark data on low-frequency sensitivity in children are minimal. This study is part of a multi-center investigation addressing a gap in knowledge on the role of low-frequency hearing in binaural sensitivity and speech recognition in noise when low-frequency binaural cues are available. We investigated age-related sensitivity to interaural time differences (ITDs) and interaural level differences (ILDs), as well as the benefit for speech understanding in children and adults with typical hearing. These data will provide developmental typical benchmarks for our team’s ongoing studies aimed at assessing clinical outcomes in children and adults who receive EAS devices. Results showed age-related improvements in both ITD/ILD thresholds and speech perception in noise across childhood. However, despite these parallel trends, the measures may reflect distinct underlying mechanisms. This work was supported by grants from the NIH-NIDCD (R01DC020194 to R.H.G. and R01DC020355 to R.Y.L) and in part by a core grant to the Waisman Center (NICHD P50HD105353).

A W crest banner flutters in the wind on Bascom Hill at the University of Wisconsin-Madison during autumn on Oct. 18, 2019. (Photo by Jeff Miller /UW-Madison)

Hearing and Donuts (Brain and Bagels) Seminar

Matt Banks, Ph.D.
Waisman Center
@ 8:30 am - 9:30 am
Learn more about the Hearing and Donuts Seminar Series

How consciousness emerges from the complex of interconnected networks in the brain is one of great unsolved mysteries in science. We seek to gain insight into this question by studying what changes in the brain during loss, recovery, and altered states of consciousness in neurosurgical patients implanted with intracranial electrodes while being evaluated for seizure resection surgery. We identify signatures of these changes by identifying common changes in brain activity and connectivity during sleep and anesthesia, two conditions in which consciousness is lost reversibly. In addition to elucidating the neural correlates of consciousness, our work is relevant to monitoring depth of anesthesia, and in the diagnosis, management and prognosis of pathological states of consciousness including central sleep disorders, delirium, vegetative or minimally conscious states, and coma.

A W crest banner flutters in the wind on Bascom Hill at the University of Wisconsin-Madison during autumn on Oct. 18, 2019. (Photo by Jeff Miller /UW-Madison)

Prosem Lecture: Auditory and Motor Timing in Healthy Aging and Neurological Disorders

Carolyn Kroger, Ph.D.
62 Goodnight Hall
@ 12:00 pm - 1:00 pm
Learn more about Prosem

Perception and action are fundamentally shaped by time. Precise timing allows us to integrate sensory information, understand speech, and coordinate movement. With healthy aging and in many neurological disorders, these timing processes become less reliable, contributing to difficulties in communication, motor control, and overall quality of life. My research investigates how aging and neurological conditions alter time perception and motor coordination, and how these changes affect auditory processing and movement. Using interdisciplinary approaches such as psychophysics, motion tracking, behavioral modeling, and electroencephalography, I study the neural and behavioral mechanisms that support auditory and motor timing. My goal is to understand how these mechanisms are impacted by healthy aging, hearing loss, and motor disorders. In this talk, I will present two main lines of research, highlighting key findings from past and ongoing work. First, I will examine the role of temporal processing in auditory feature integration across the lifespan. Second, I will discuss how aging and neurological disorders affect rhythm perception and movement timing. I will conclude by outlining how my future work will advance our understanding of human timing in healthy older adults and inform rhythm-based interventions to improve speech and movement fluency in motor and communication disorders.

Carolyn Kroger, Ph.D.

Job Talk: Reframing Language Rehabilitation as a Sleep-Dependent Learning Process to Enhance Healthy Aging

Emily Goldberg M.S., CCC-SLP
62 Goodnight Hall
@ 4:00 pm - 5:00 pm
Learn more about Prosem

Aphasia is a chronic language disorder that disproportionately affects older adults following stroke, with profound consequences for communication, independence, and quality of life. Although behavioral language therapy is the clinical standard for managing aphasia, treatment outcomes vary widely, and mechanisms supporting successful language re-learning remain poorly understood. Because rehabilitation depends on learning and memory processes, identifying biological factors that support or constrain learning is critical for improving aphasia outcomes. I present a program of research that reframes aphasia rehabilitation as a sleep-dependent learning process at the intersection of communication science, cognitive neuroscience, and healthy aging. Sleep disturbance is common after stroke and changes systematically with age, yet sleep has been overlooked as a contributor to aphasia recovery. Drawing on behavioral, neuroimaging, and sleep data from individuals with chronic post-stroke aphasia, I introduce a neurobiological model proposing complementary hippocampal and neocortical routes to language re-learning. I then describe ongoing work testing this model by examining associations between sleep quality and treatment-driven changes in language function and neural organization. Finally, I outline future directions that integrate sleep physiology into aphasia rehabilitation and extend these principles to healthy aging, positioning sleep as a modifiable mechanism for promoting learning and plasticity across the lifespan.

Emily Goldberg MS, CCC-SLP

Job Talk: Considering Public Health Principles of Screening to Advance Hearing Health Care

Lauren Dillard, Ph.D., Au.D., M.S.
62 Goodnight Hall
@ 12:00 pm - 1:00 pm
Learn more about Prosem

This presentation is guided by a public health framework of the principles that should be met to recommend screening for any disease or condition, including age-related hearing loss (ARHL). Dr. Dillard will provide an overview of her research contributing to the evidence base to support several principles related to screening for ARHL, including (1) the natural history should be understood, (2) treatment should be accepted and better at an earlier stage and (3) there should be an agreed upon policy on whom to treat. Key results towards each of the principles are as follows. First, declines to hearing occur across the entire adult lifespan and vary by key demographic and health-related risk factors; improved understanding on the natural history of ARHL can inform understanding on when to begin screening and treatment. Second, rates of hearing aid uptake among the general population are low; preliminary suggest that earlier intervention could improve long-term hearing aid outcomes. Third, tools of self-reported hearing difficulty may be beneficial in determining whom to treat. In addition, Dr. Dillard will present data on the outcomes of a large-scale program to screen for ARHL and future research directions aiming to maximize the impact of screening for ARHL.

Lauren Dillard, Ph.D., Au.D., M.S.

Hearing and Donuts (Brain and Bagels) Seminar

Erik Jorgensen, Au.D, Ph.D., CCC-A
Waisman Center
@ 8:30 am - 9:30 am
Learn more about the Hearing and Donuts Seminar Series

Hearing loss is robustly associated with increased risks of loneliness and depression. The mechanisms underlying this association are unknown. Whether interventions such as hearing aids reduce risk of negative psychosocial health outcomes is equivocal, but the research is limited. In this talk, we outline a possible hearing-related behavior framework for understanding how hearing loss may lead to negative psychosocial health outcomes. Rooted in auditory ecology, we posit that hearing loss leads to negative psychosocial health outcomes due to mismatches between perceptual abilities and auditory demands of listeners, such that hearing loss differentially effects psychosocial health dependent on soundscapes listeners experience. We then provide empirical evidence testing this theory. Our results provide support for our hypothesized pathway from hearing loss to depression; however, the results also suggest that hearing aid use may change daily life behaviors in fundamental ways that call into question traditional philosophies of hearing aid benefit and outcome.

Erik Jorgensen, Au.D, Ph.D.

Prosem Lecture: The Speech of Speech-Language Pathologists: How SLPs’ Speech Style Impacts Children’s Language Outcomes

Liz Ancel, Ph.D., CCC-SLP
150 Russell Laboratories
@ 12:00 pm - 1:00 pm
Learn more about Prosem

In speech-language pathology, clinicians often conduct assessment and intervention tasks with children via live voice. When administering these tasks, SLPs may differ in their manner of delivery, even when the content of the task is the same. Based on previous research in child-directed speech (speech directed to children), variability between SLPs' manner of delivery potentially impacts children's language outcomes. However, many findings from existing research in child-directed speech have limited generalizability to clinical settings in speech-language pathology due to their focus on caregiver speech and broad, long-term language outcomes. To better understand the function and role of speech characteristics in clinical settings with children, this presentation will first describe the speech of 31 SLPs administering a common clinical task (sentence repetition) to an imagined adult listener and four imagined child listeners who differ in age and language ability. Then, we will analyze how three different SLPs' usage of adult-directed and child-directed speech impacted children's ability to repeat sentences accurately. The results demonstrate how SLPs' manner of delivery can impact children's language outcomes, which furthers the need for research connecting speech characteristics and child outcomes that encompasses a variety of clinical tasks and child populations.

Liz Ancel, Ph.D.