Hearing and Donuts (Brain and Bagels) Seminar
September 27 @ 8:30 am - 9:30 am
Presenter: Corinna Burger, Ph.D., Professor of Neurology, University of Wisconsin-Madison
Topic: Mechanisms of Successful Cognitive Aging
Environmental enrichment (EE) preserves cognition in the senescent brain, and although humans with high cognitive activity have a lower risk for Alzheimer’s disease, little is known concerning mechanisms giving rise to the functional benefits of EE. To explore potential mechanisms underlying the beneficial effects of EE, we have exposed both young and aged rats to EE and shown that they display enhanced cognitive ability, synaptic plasticity and metabotropic glutamate receptor signaling in the hippocampus when compared to rats exposed to social enrichment or standard housing conditions.