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Hearing and Donuts (Brain and Bagels) Seminar
September 24, 2021 @ 8:30 am - 9:30 am
Presenter: Phil Smith, Department of Neuroscience, UW Madison
Topic: Just say N.O.! Nitric oxide and its effects in the cochlear nucleus
Nitric oxide (NO) is a gas that was made famous by its ability to cause smooth muscle relaxation and thus dilation of blood vessels. Besides acting on blood vessels NO also has effects on certain neurons in the central nervous system and in the hippocampus is involved with some forms of long-term potentiation (LTP) that is often associated with learning and memory. In the auditory system some believe that NO may be involved in the generation of tinnitus and/or presbycusis. I will talk about a set of cells in the cochlear nucleus known as T-stellates that are capable of synthesizing and releasing NO and will describe some of the circuit changes generated by this NO.